Approximate effective sample size from GWAS of related samples
Neff(raf, seB, Vy = 1)
| raf | vector of reference (or minor) allele frequencies for all SNPs in the GWAS |
|---|---|
| seB | vector of standard errors of SNP effect estimates, in same order as SNPs in raf |
| Vy | trait variance; default is 1 under assumption trait is transformed to a standard Normal distribution |
Estimate of effective sample size