internal function for multibeta, modified from JAM_PointEstimates_Package_Simplified of R2BGLiMS package

Source: R/prep.R

internal function for multibeta, modified from JAM_PointEstimates_Package_Simplified of R2BGLiMS package

JAM_PointEstimates_Xcov(marginal.betas = NULL, Xcov = NULL, raf, n, ybar)

Arguments

marginal.betas

vector of single snp effect estimates from GWAS
Xcov

genotype covariance matrix
raf

vector of reference allele frequencies
n

sample size of GWAS
ybar

trait mean

Value

joint effect estimates of snps