internal function for multibeta, modified from JAM_PointEstimates_Package_Simplified of R2BGLiMS package (Paul Newcombe)

internal function for multibeta, modified from JAM_PointEstimates_Package_Simplified of R2BGLiMS package (Paul Newcombe)

JAM_PointEstimates_updated(marginal.betas = NULL, X.ref = NULL, n = NULL, ybar)

Arguments

marginal.betas

vector of single snp effect estimates from GWAS

X.ref

genotype matrix

n

sample size of GWAS

ybar

trait mean

Value

joint effect estimates of snps